Mystery cells, case #5

This week’s mystery cell case is a 37 year old woman with a decreased platelet count seen in the Hematology clinic at Hamilton Regional Laboratory Medicine Program (HRLMP) in Canada. The sample was run on one of the five CellaVision DM96 analyzers used within the health network.

Thank you Wendy Patterson, Senior Morphology Tech in the Malignant Hematology Lab, for sharing the case with us! The diagnosis will be announced next week.

What diagnosis do you suspect? Please share your thoughts on our blog!

Click to enlarge the cells.

Find out how HRLMP offers quicker turnaround time for blood tests here

Posted on by CellaVision News Blast | Tagged | 31 Comments

31 Responses to Mystery cells, case #5

  1. avatar Ellie Hughes says:

    Many times the body will repair itself and produce more platelets if
    given the needed rest from these foods. A�Some other researchers believe that a possible viral infection
    could have initiated the whole thing. It will not
    really help the bone marrow produce more platelets.

  2. avatar Sandra Dorland, St. Joseph's Hospital, Phoenix, Az says:

    It is a May Heggelin anomaly.
    Dohle bodies and giant platelet

  3. avatar Terese Russell says:

    May-Hegglin Anomaly :)

  4. avatar Silvia Trainor says:

    Looks very much like May-Hegglin anomaly with the giant platelets and Döhle bodies.

  5. avatar Serena says:

    Definately May-Hegglin anomaly.

  6. avatar Sheila Ryken says:

    Definitely May-Hegglin anomaly

  7. avatar florence says:

    May hegglin anomaly with Dohle body

  8. avatar Luba says:

    What would lab life be without humor!? Love it! But seriously, I believe it’s May-Hegglin Anamoly :)

  9. avatar Jeffrey C. Ulep says:

    Definitely a May-Hegglin anomaly

  10. avatar Jeffrey C. Ulep says:

    giant platelets containing few granules with cytoplasmic inclusion bodies, is definitely May-Hegglin anomaly

  11. avatar Kumar says:

    Such a beautiful morphologic features.
    A clear cut of dohle bodies in the cytoplasm of neutrophils associated
    with giant platelets and thrombocytopenia.
    Suggestive of May-Hegglin Anomaly.
    From: Kumar, MAHSA U.C, Malaysia

  12. avatar Peter says:


  13. avatar Steve Johnson says:

    Giant platelets and spindle shaped Dohle bodies in neutrophils – May Hegglin anomaly

  14. avatar JOHN PETERS says:

    As mentioned above – May-Hegglin with giant platelets and neutrophil inclusions. A good example.

  15. avatar Paula Perry says:

    I agree with everyone else, it appears to be May-Hegglin anomaly.

  16. avatar Rose markarian says:

    May-Hegglin Anomaly

  17. avatar Jennifer Melville says:

    May-Hegglin anomaly

  18. avatar marionette cortez says:

    Giants platelets;Dohle inclusions on the neutrophilic band;it is a May-Hegglin Anomaly

  19. avatar mark lewis says:

    The presence of giant platelets and dohle bodies within the neutrophils would suggest May-Hegglin anomaly.

  20. avatar Vipul Shah, MT, H(ASCP); DLM(ASCP) says:

    Undoubtably May-Hegglin anomaly.

  21. avatar Xiaobo Hu says:

    May-Hegglin anomaly

  22. avatar Jo Linssen says:

    Giant platelets and leukocyte inclusions and Döhle bodies and normal erythrocytes morphology (DD-MDS), therefore a May-Hegglin anomaly.

  23. avatar Jo Linssen says:

    A May-Hegglin Anomalie

  24. avatar Regitze Reumert says:

    It is May-Hegglin anomaly it resemble Döhler bodies but large – giant platelets is seen in approximately one-third af patients with May-Hegglin anomaly.

  25. avatar Saeed azad says:

    May-Hegglin Anomaly

  26. avatar Ragnheidur Jonsdottir says:

    May-Hegglin anomaly

  27. avatar Helle B. Hager says:

    Large inclusions resembling Döhle bodies and giant plateles – May-Heggelin anomaly.

  28. avatar Margit Grome says:

    Could be May-Hegglin Anomaly or Bernard-Soulier Syndrome. But since there are Döhle bodies randomly distributed in the granulocytic cells – I wote for May-Hegglin Anomaly. Thank You for an interesting case ;O)

  29. avatar Leif Cory Nielsen says:

    It is a May Heggelin anomali.
    Doehle bodies and giant platelet

  30. avatar Kaoru Tohyama, MD, PhD, Japan says:

    At a glance, it must be May-Hegglin anomaly.

Leave a comment

Your email address will not be published. Required fields are marked *

Please read our privacy policy before posting.

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>