We are glad to see that you are sharing your suggestions despite the limited information we could present for this case.
The patient was diagnosed with Burkitt’s Lymphoma, a cancer of the lymphatic system that has an especially high incidence in equatorial Africa among children 3 to 16 years of age. The disease is characterized by tumors of the jaw bones and abdomen and is named after Denis Burkitt, who mapped its peculiar geographic distribution across Africa in the 1950s.
There are three main clinical variants of Burkitt’s Lymphoma and they cannot really be distinguished from one another based on microscopic morphology. All types of Burkitt’s lymphoma are characterized by a disregulation of the c-myc gene by one of three chromosomal translocations on the gene found at 8q24 with the most common variant being a translocation being t(8;14)(q24;q32). Localized tumors respond well to chemotherapy and can have a very good prognosis. Involvement of the central nervous system, however, can lead to a far more serious prognosis.
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Mystery cells case #17 presents a CSF sample of an unknown patient. The sample was analyzed using the CellaVision Body Fluid Application. Based on the image below, what diagnosis do you think was given?
CellaVision is this year’s winner of PhotonicSweden’s industry award for its contribution to the laboratory medicine industry due to its technology strength within the field of Optics and Photonics and successful business development. The award is a great tribute to our CellaVision team!
The jury’s motivation: CellaVision is the world leader in digital microscopy used for hematology. Since it was founded in 1994, it has developed into an important player in the field of laboratory medicine and the company supplies its product to commercial laboratories and hospital laboratories all over the world. CellaVision is well on the way in establishing a global standard for digital microscopy.[…]
The prize was handed to CEO Yvonne Mårtensson by PhotonicSweden’s Magnus Breidne at a ceremony last week at the conference on Optics and Photonics in Uppsala, Sweden.
Take part of the full story here.
While running a routine cell image check we stumbled across this odd looking cell. Among all the thousands of cells we have in our digital cell library this was the only one looking like this. For us this was quite a rare finding.
Have you seen cells looking like this?
A new study highlights operational efficiencies and improved consultation capabilities for smaller laboratories using the new CellaVision Image Capture System for their white blood cell differential on peripheral blood smears.
“The major advantage of the CellaVision Image Capture System is the possibility for smaller laboratories to digitise their samples and have the analysis performed at the main lab or at another remote location. This allows for a 24 h morphological expert system in the routine laboratory in which slide transportation to the main laboratory can be eliminated”, says Dr Anja Leyte who performed the study at the OLVG Hospital in Amsterdam.
- A reliable and accurate tool in the differential WBC count on peripheral blood smears
- Provides small laboratories with a 24 h available real-time digital differential WBC count
- Provides consultation for patients in remote locations
Link to abstract and full story at publisher’s website
Clinical performance evaluation of the CellaVision Image Capture System in the white blood cell differential on peripheral blood
Simone M Smits, Anja Leyte
Haematological Clinical Chemistry Laboratory, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
Journal of Clinical Pathology (doi:10.1136/jclinpath-2013-201737)