Cell Case #18

This Cell Case presents a 45 year old male. He was admitted to the emergency ward with dizziness and dyspnoe d'effort.


Smudge cells – include or exclude?

Increased focus is placed on the importance of smudge cells in connection with certain types of diagnoses. A number of articles explore this subject and according to the article Percentage of Smudge Cells on Routine Blood Smear Predicts Survival in Chronic Lymphocytic Leukemia the writers suggest that the number of smudge cells may have important biologic correlations ...


Diagnosis mystery cells case #17: Burkitt’s Lymphoma

We are glad to see that you are sharing your suggestions despite the limited information we could present for this case. The patient was diagnosed with Burkitt’s Lymphoma, a cancer of the lymphatic system that has an especially high incidence in equatorial Africa among children 3 to 16 years of age. The disease is characterized by ...


Mystery cells, case #17

Mystery cells case #17 presents a CSF sample of an unknown patient. The sample was analyzed using the CellaVision Body Fluid Application. Based on the image below, what diagnosis do you think was given?


A rare cell with both eosinophilic and basophilic granules

While running a routine cell image check we stumbled across this odd looking cell. Among all the thousands of cells we have in our digital cell library this was the only one looking like this. For us this was quite a rare finding. Have you seen cells looking like this?


Diagnosis mystery cells case #16

As you suspected the little girl was diagnosed with Chédiak-Higashi syndrome. The patient had a sister that was a match for a bone marrow transplant, while that will help the functionality of the neutrophils, the patient will be left with peripheral neuropathy. We found another case report with the Chédiak-Higashi syndrome in the American Journal ...


Mystery cells case #16: Female infant with grey hair

This case presents a 1 ½ year old Asian female that came to the hospital with an infection and high fever. Her hair was of a gray color and her skin was pale and gray. What can you see when you look at the cells?  Thank you to the hospital in the Western United States for ...


A young woman with relapsed/refractory anaplastic large cell lymphoma in leukemic phase

Our readers continue to provide us with interesting and informative cases about cell morphology. This week’s case was sent to us by Beth Ward, MT ASCP at Cincinnati Children’s Hospital Medical Center in Ohio, USA. Here is her story: Patient history This is a story about a young woman with relapsed/refractory anaplastic large cell lymphoma ...


The diagnosis for mystery case #15

Great interest and many good comments on this case! His diagnosis was:  Eosinophilic meningitis secondary to Angiostrongylus cantonensis infection. Angiostrongylus cantonensis is a parasitic nematode (roundworm) which causes angiostrongyliasis, the most common cause of eosinophilic meningitis in Southeast Asia and the Pacific Basin. The nematode commonly resides in the pulmonary arteries of rats, giving it the nickname rat lungworm. Humans are incidental ...


Mystery cells, case #15

Who can tell the diagnosis? A 50-year-old male from the State of Nevada was sailing his boat in the South Pacific for over a month. He would frequently eat raw shellfish and raw fish. He presented to a hospital in Nevada with muscle pain, numbness and headache. A spinal fluid aspiration was done and the ...


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