2016-12-07

Cell Case #21

This Cell Case presents a 64-year-old man that arrived at an emergency ward with complaints of malaise and fatigue. Clinical chemistry parameters showed a total protein of 126 g/L, an albumin of 26 g/L and a total IgG of around 70 g/L.  Peripheral blood smear analysis displayed several aberrant cell types.

22a

What diagnosis do you think was given in this case? Please post your suggestion!

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/ The CellaVision Blog Team


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This blog is created by CellaVision for laboratory professionals with a particular interest in hematology and digital cell morphology. Our aim is to inform, educate and inspire in equal measures – by highlighting interesting articles, sharing interesting patient cases and cell images, and presenting inspiring success stories from our community of CellaVision-users from around the world.

31 thoughts on “Cell Case #21”

  1. Immature Plasma Cell:
    Clear Golgi area around nucleus.
    Nuclear chromatin is too immature to be identified as a mature plasma cell.

  2. Multiple myeloma. The presence of plasma cells, a paraprotein elevated in
    }
    serum (Rouleaux in blood smears) and decreased albumin. .Astenia and weakness due to decreased red blood cell count: anemia. The patient’s height may be reduced by several centimeters as a result of vertebral crushing.

  3. Rouleaux, increased protein and what looks like a plasma cell (albeit not totally typical in shape). I’d go for some plasma cell disorder possibly Myeloma.

  4. Myeloma is the most likely diagnosis. This is apparently large a plasma cell. The elevated immunoglobulin levels are causing the RBC rouleaux that is also noted in the picture.

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