The diagnosis for mystery case #7
The patient was from Africa, and she had been tested HIV-positive.
The cells in row 4 were not WBC’s – but Cryptococcus. As many of you recognized!
The patient was very ill when she came to the hospital, and it took several months to cure her from the Cryptococcus infection.
Cryptococcus is a type of yeast, which has a capsule surrounding the cell.
The organisms are round to oval yeast-like fungi from 3,5 to 8 µm in size, with a thick mucopolysaccharide capsule. The capsule is often visible as a clear area around a central core.
Thank you Margit Grome and Lennarth Friis-Hansen for sharing this case!
The image below shows a monocyte digesting Cryptococcus.