Mystery cells, case #5

This week’s mystery cell case is a 37 year old woman with a decreased platelet count seen in the Hematology clinic at Hamilton Regional Laboratory Medicine Program (HRLMP) in Canada. The sample was run on one of the five CellaVision DM96 analyzers used within the health network.

Thank you Wendy Patterson, Senior Morphology Tech in the Malignant Hematology Lab, for sharing the case with us! The diagnosis will be announced next week.

What diagnosis do you suspect? Please share your thoughts on our blog!

Click to enlarge the cells.

Find out how HRLMP offers quicker turnaround time for blood tests here

31 thoughts on “Mystery cells, case #5”

  1. Many times the body will repair itself and produce more platelets if
    given the needed rest from these foods. A�Some other researchers believe that a possible viral infection
    could have initiated the whole thing. It will not
    really help the bone marrow produce more platelets.

  2. giant platelets containing few granules with cytoplasmic inclusion bodies, is definitely May-Hegglin anomaly

  3. Such a beautiful morphologic features.
    A clear cut of dohle bodies in the cytoplasm of neutrophils associated
    with giant platelets and thrombocytopenia.
    Suggestive of May-Hegglin Anomaly.
    From: Kumar, MAHSA U.C, Malaysia

  4. Giant platelets and leukocyte inclusions and Döhle bodies and normal erythrocytes morphology (DD-MDS), therefore a May-Hegglin anomaly.

  5. It is May-Hegglin anomaly it resemble Döhler bodies but large – giant platelets is seen in approximately one-third af patients with May-Hegglin anomaly.

  6. Could be May-Hegglin Anomaly or Bernard-Soulier Syndrome. But since there are Döhle bodies randomly distributed in the granulocytic cells – I wote for May-Hegglin Anomaly. Thank You for an interesting case ;O)

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