Summary of the global test: Biphenotypic Acute Leukemia

Thank you for trying out the global cell morphology test!

Over 100 of you completed the test and you seem to agree on many things but there are also a few interesting findings to discuss.

You were divided into two different groups and the average WBC agreement was 83% when comparing to the majority. One person managed to get a 100% agreement compared to the Examiner.

Cells that caused you some problems are the two cells shown below. Those cells got a lot of different suggested classifications by the two groups.

Suggested classifications: Metamyelocyte, Myelocyte, Promyelocyte, Promonocyte, Lymphocyte, Lymphocyte variant from, Monocyte, Large granular lymphocyte.

Suggested classifications: Myelocyte, Metamyelocyte, Promyelocyte, Monocyte, Promonocyte, Lymphocyte, Prolymphocyte, Lymphocyte variant form, Smudge cell.

Patient case summary

  • Biphenotypic Acute Leukemia (BAL), with the Philadelphia translocation.
  • Complete remission; planned allogeneic bone marrow transplantation.
  • Now remitted with strong bone pain.
  • Treated with high-dose morphine and serenase.
  • WBC reached 60 10^9 /L probably due to Zarzio. Zarzio contains the active ingredient, filgrastim. Filgrastim is a copy of a substance normally present in your body, called Granulocyte Colony Stimulating Factor (G-CSF).

For those of you that participated you can now log in to your account and see the result for your group.

Let us know what you thought about this activity and if your lab has an interesting slide that you want to share in the next global test.


2 thoughts on “Summary of the global test: Biphenotypic Acute Leukemia”

  1. I have participated at the global test. How and where can I log in to see the results of my group.
    I have received already a message that I had an agreement of 93% compared with the Examiner.

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