Metastatic carcinoma of the pituitary gland

A 71 year old woman presented with a 3 week history of weight loss, nausea, vomiting and severe depression. Physical examination disclosed no abnormalities. Her past medical and family history was unremarkable. Standard laboratory tests including electrolytes were normal. In order to detect the reason for her symptoms extensive diagnostic procedures (CT-Scans, endoscopy of the ...


Detecting leptomeningeal spread of AML

Conditioning procedures prior allogeneic stem cell transplantation aim on the eradication of all malignant cells as the prerequisite for cure. However many drugs used for conditioning do not reach all anatomical compartments, since these are separated by a special structure and are therefore called “sanctuary sites”. This is particularly true for the central nervous system ...


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