Early diagnosis of leukemia in a child with Down syndrome

A 4-year-old child with Down syndrome came to the Albert Schweitzer Hospital in Dordrecht for a routine check-up with his pediatrician. In our lab, blood cell counts showed a normal hemoglobin level (7.4 mmol/L; 11.9 g/dL), mild thrombo-cytopenia (platelet count 98 x 109/L) and a normal leukocyte count. Morphological analysis of the peripheral blood smear ...

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